Why is NMN supplementation recommended for men starting at age 40?

What does 40 mean for a man?

The age of 40 is an important turning point in the development of the male body function.

From this age onwards, NAD + levels in men begin to quietly decline.

NAD+ plays a central role in cellular energy metabolism and is a necessary coenzyme for mitochondrial oxidative phosphorylation and production of adenosine triphosphate (ATP).

Reduction of NAD + levels

With increasing age, the decrease of NAD+ directly impacts mitochondrial function and greatly reduces cell productivity efficiency.

Just as a car engine reduces fuel efficiency and lacks power due to wear and tear of components, the human body is also prone to fatigue due to a decline in energy metabolism.

Men after the age of 40 will significantly find that after the same intensity of exercise or work, the body recovers longer than in their 20s, and the recovery of energy becomes slower.

NMN, as a precursor of NAD+, can be taken up by cells and converted into NAD+, injecting "power" into cell energy metabolism, effectively improving the energy shortage caused by age, and helping men maintain vigorous energy.

In addition to changes in cellular energy metabolism, men's DNA repair ability also gradually decreases after the age of 40.

The DNA of the human body is always faced with a variety of endogenous (such as free radicals produced during metabolism) and exogenous (such as ultraviolet radiation, environmental pollution, etc.) factors.

In order to maintain the stability of the genome and the normal function of the cell, the cell has a complex and precise DNA repair mechanism.

In this mechanism, NAD + is an important substrate for some key repair enzymes, such as the PARP enzyme family.

When NAD+ is sufficient, the repair enzyme can operate efficiently and repair damaged DNA in time.

However, with age, the level of NAD+ decreased, and the activity of DNA repair enzyme was suppressed, resulting in the gradual accumulation of DNA damage.

For human cells, this increases the risk of genetic mutations, which are closely linked to the development of age-related diseases such as cancer and neurodegenerative diseases.

Supplementing NMN can increase the level of NAD + in the body, provide sufficient material support for the DNA repair process, activate the activity of related repair enzymes, and help maintain the integrity of the cell genome.

This is like providing sufficient "raw materials" and "tools" for DNA repair work, so that cells can more effectively repair damaged DNA, reduce the possibility of disease caused by the accumulation of DNA damage, so as to lay a solid foundation for men's physical health.

Since the age of 40, the male body has encountered challenges in many aspects such as physiology, health risks and life pressure, and NMN is like a key to help health, bringing potential benefits to men's health from multiple dimensions, and becoming a powerful "ally" to protect middle-aged men's health.

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