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Improvement of NMN on 5 major senile diseases

Source:syn bio world Date:(2025-02-07)Category:synbioSize: Large Middle Small

Improvement of NMN on 5 major senile diseases

NMN can be converted into NAD+ in vivo, which in turn activates Sirt1 protein, which has a potential improvement effect on a variety of age-related diseases.


01 Cardiovascular Disease



Improve vascular endothelial function



NMN can increase the level of NAD+ in the body, promote the production of nitric oxide by vascular endothelial cells, relax blood vessels, reduce blood pressure, and reduce the burden on the heart.



Reduce oxidative stress



It can enhance the activity of antioxidant enzymes in cells, remove free radicals, reduce oxidative damage, and reduce the risk of atherosclerosis.



Regulate blood lipids



By influencing the expression of genes associated with lipid metabolism, NMN helps regulate blood lipid levels and reduce the deposition of cholesterol and triglycerides.


02 Alzheimer's disease



Enhance neuron energy metabolism



Provide sufficient energy for brain neurons, maintain their normal function, and reduce the damage and death of neurons caused by insufficient energy.



Promotes neurotransmitter synthesis



Improve the synthesis and release of neurotransmitters such as acetylcholine, improve nerve signaling, and enhance cognitive function.



Inhibit neuroinflammation



Reduces the inflammatory response in the brain, reduces the damage of inflammatory factors to neurons, and slows the progression of Alzheimer's disease.


03 Diabetes



Improve insulin sensitivity



It makes the body's cells more sensitive to insulin and promotes the uptake and use of glucose by the cells, thus better regulating blood sugar levels.



Improve pancreatic β cell function



Protect islet beta cells, promote the normal secretion of insulin, and maintain the stability of blood sugar.



Regulates genes related to glucose metabolism



By regulating the gene expression related to glucose metabolism, the process of glucose metabolism can be optimized and the disorder of glucose metabolism can be reduced.


04 Osteoporosis



Promote osteoblast differentiation



Stimulate the activity of osteoblasts, promote the synthesis and mineralization of bone matrix, and increase bone density.



Inhibition of osteoclast activity



Reduce the absorption of osteoclasts to bone tissue and maintain the balance of bone mass.



Regulates bone metabolic signaling pathways



Participate in the regulation of bone metabolism-related signaling pathways to promote healthy bone development and maintenance.


05 Macular degeneration



Protective retinal cells



Increase the level of NAD+ in retinal cells, enhance the antioxidant capacity and energy metabolism of cells, and reduce the damage and death of retinal cells.



Improve retinal blood circulation



Promote the health of retinal blood vessels, improve blood circulation, and provide adequate nutrition and oxygen to the retina.



Inhibit inflammation



Reduce the inflammation of the retina, reduce the damage of inflammation to the retina, and protect vision.

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