Reveal the magical effect and action of pyrroloquinoline quinone PQQ

In the exploration of the mysteries of nature, scientists continue to discover surprising substances, and pyrroloquinoline quinone (PQQ) is one of them, this once involved in the origin of life on Earth mysterious substances, now known as the "king of immunity", with a variety of beneficial physiological effects on the human body.

What is PQQ?

PQQ, also known as Pyrroloquinoline quinone, is a coenzyme of REDOX enzyme and an essential nutrient for human body. Its unique structure of o-quinone makes it significantly different from other coenzymes. PQQ is widely distributed in nature, exists in soil and is synthesized by microorganisms in soil.

Plants pass PQQ to us by absorbing it, and bacteria in some fermented foods and beverages can also produce PQQ, which is found in various tissues of the human body, especially in breast milk, and is an essential factor for healthy infant development.

Efficacy and function of PQQ

1. Promote growth and immunity

PQQ is known as an indispensable "growth factor" for the growth of various organisms, in addition, PQQ is essential for immunity, and studies have shown that insufficient PQQ may lead to immune cell dysfunction and reduce the body's immune capacity.

2. Antioxidant capacity

PQQ has a strong antioxidant capacity, which can effectively remove peroxides and protect mitochondria from oxidative damage. It can also inhibit lipid peroxides and protect cardiomyocytes from ischemia and reperfusion damage. PQQ can also protect the heart from myocardial ischemia and myocardial infarction, avoid severe shock in animal models, and prevent cerebral ischemia and hypoxia. Promotes recovery from spinal cord injury, thereby preventing severe shock in animal models.

3. Neuroprotective effect

PQQ can improve the neuronal damage caused by oxygen and sugar deprivation, reduce the change of Nishi body content caused by D-galactose treatment, and weaken the nerve damage caused by amyloid beta. PQQ can also significantly improve the memory function of rats, and has obvious effects on memory preservation and dementia prevention.

4. Liver protection

PQQ can protect the liver against liver injury induced by alcohol and carbon tetrachloride and liver fibrosis induced by TAA. It can increase the chlorophyll content of winter wheat flower leaves, strengthen photosynthesis and increase grain yield.

5. Anti-inflammatory and immune regulation

PQQ can clear ROS and counteract the inflammatory damage caused by oxidative stress. When PQQ is lacking in the diet, the content of interleukin in mice is significantly reduced. When PQQ is added in the diet, the spleen cells respond better to mitogen A and LPS, and the number of lymphocytes in lymphocyte accumulation can be increased. The integrity of the lymphatic organs associated with the intestine was restored to a certain extent.

6. Growth factor-like effects

PQQ can significantly improve the skin weakness, thinning and flaking of hair, and severe arcuation and curvature of the body of the young mice. When the mother supplements the appropriate amount of PQQ, the growth of the young mice and the fertility and behavior of the female mice tend to be normal, which indicates that PQQ is an essential nutrient factor for the growth and development of young animals.

7. Activate the macrobiotic protein family

PQQ can protect cells and delay the aging process by activating SIRT1, SIRT3, and SIRT6, long-life proteins that are members of the NAD+ dependent deacetylated protein family and are believed to be key factors in defending against oxidative stress, inflammation, and aging.

8. Optimize mitochondrial function

PQQ, through its synergistic effect with NAD+ and activation of the longevity protein family, helps to enhance and optimize the function of mitochondria and improve the energy metabolism of cells, which is of great significance for maintaining physical health and delaying aging.

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