Many clients experience improved sleep quality after taking NMN for a period of time. Let's take a full and detailed look at the possible rationale behind it.
1. Regulation of biological clock:
As a precursor to NAD+, NMN is able to increase the level of NAD+ within cells, which is essential for maintaining a normal biological clock and sleep cycle.
Studies have shown that NAD+ regulates many sleep-related genes in cells, such as PER2 and CRY1, which play a key role in regulating the circadian clock and sleep.
As we age, NAD+ levels gradually decline, which can lead to circadian dysfunction, which can lead to sleep disorders. Supplementing with NMN helps regulate the body clock and improve sleep quality.
2. Enhancement of energy metabolism:
NMN promotes energy metabolism in cells by increasing NAD+ levels, which helps maintain a normal sleep cycle.
Good energy metabolism can ensure that the body is fully rested and restored during sleep, thus improving the quality of sleep.
3. Improvement of DNA repair ability:
Sleep is a critical time for the body to do DNA repair and maintenance. NMN helps maintain healthy cell function by increasing NAD+ levels and improving DNA repair, which may improve sleep quality.
4. Enhancement of antioxidant defenses:
The intake of NMN can enhance the antioxidant defenses of cells and reduce the negative effects of oxidative stress on sleep.
Some studies have found that oxidative stress can interfere with the normal functioning of the body clock, leading to sleep problems. NMN helps to maintain the stability of the biological clock and improve sleep quality through its antioxidant effect.
5. Clinical trial results:
In December 2022, a research team from Southern University of Science and Technology published a paper in the American Journal of Translational Medicine, showing that NMN can significantly shorten the time to fall asleep, increase the time of rapid eye movement and deep sleep, and improve sleep quality.
In June 2022, a study published in Glycative Stress Research by Yonei's team at Doshisha University in Japan found that, after eight weeks of oral ingestion, Improved sleep (better sleep, less difficulty falling asleep, better wakefulness in the morning), improved fatigue (less fatigue, faster recovery from fatigue, better mobility, faster laps, less muscle pain after exercise).
6. Application of middle-aged and elderly people:
Many elderly people often have sleep problems due to the fragile body clock, easy to be disturbed, and decreased levels of NAD+ in the body. Supplementing with NMN can fundamentally strengthen the stability of the biological clock and improve adaptability, thereby improving the quality of sleep in the elderly.
NMN significantly improves sleep quality by regulating the biological clock, enhancing energy metabolism, improving DNA repair capacity, enhancing antioxidant defense, and clinical trials. Especially for the elderly, the supplement of NMN is of great significance for improving their sleep quality.
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