Why do many people say that NMN can solve hair loss

NMN is considered to have a potentially positive role in addressing hair loss, mainly due to its effect on NAD+ levels. Today, Xiaobian will take you to understand its principle in detail and related research.

1. Improve NAD+ level:

NMN is the precursor of NAD+, and by supplementing NMN, the level of NAD+ in cells can be significantly increased. With age, NAD+ levels gradually decline, which can cause the hair mother cell to not have enough ATP (adenosine triphosphate) for the protein synthesis of hair, which in turn exacerbates the hair loss problem.

2. Promote hair growth:

Studies have found that NMN supplementation can promote hair growth. In a human trial, continuous supplementation of NMN increased the amount of new hair growth in subjects, and the hair became thick and shiny, reducing hair loss.

3. Improve hair follicle health:

NMN affects not only the growth of hair, but also the health of hair follicles. The results of the study showed that the NMN treatment group demonstrated faster hair follicle growth, darker hair follicle color, more hair follicles, and larger hair follicle size. This suggests that NMN has a positive effect on hair follicle health, helping to tackle hair loss at its root.

4. Promote dermal cell proliferation:

Cytokines secreted by human dermal cells (HDPCs) play an important role in the hair growth cycle. NMN can promote the proliferation of dermal cells and repair hair follicle damage caused by DHT (dihydrotestosterone), thus slowing the process of hair loss.

5. Antioxidant protection:

NMN can enhance the body's antioxidant defense system, reduce the damage of oxidative stress to hair follicle cells, and protect the health of hair follicles. This is important for alleviating hair loss caused by oxidative stress.

6. Improve metabolic disorders:

By boosting NAD+ levels, NMN helps to improve insulin resistance caused by a high-sugar diet and regulate androgen levels, thereby mitigating their negative effects on hair follicles. This can help to address the root causes of hair loss caused by metabolic disorders.

7. Promote hair follicle regeneration:

NAD+ is involved in the regulation of cell cycle and DNA repair, and NMN supplementation may promote the activation and proliferation of hair follicle stem cells, which is conducive to the repair and regeneration of damaged hair follicles. This provides a new treatment idea for patients with hair loss.

NMN addresses hair loss by enhancing NAD+ levels, promoting hair growth, improving hair follicle health, promoting dermal cell proliferation, antioxidant protection, improving metabolic disorders, and promoting hair follicle regeneration, among other mechanisms.

A paper entitled "Beta-Nicotinamide Mononucleotide Promotes Cell Proliferation and Hair Growth by Reducing Oxidative damage" was published in the internationally authoritative journal Molecules In a study article in Stress., domestic researchers found that NMN supplementation can promote hair growth.

References:

Chuntao Xu , Jiawei Dai , Hongxia Ai， et. al. β-Nicotinamide Mononucleotide Promotes Cell Proliferation and Hair Growth by Reducing Oxidative Stress. Molecules. 2024 Feb 8;29(4):798. doi: 10.3390/molecules29040798. PMID: 38398550.

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